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More recently, Gibb et al . (1978) carried out an extensive comparison of 3 β -HSDs from human fetal membranes and placentas. The activities in chorion and placenta were very similar with respect to subcellular localization, specific activity, substrate specificity, nucleotide specificity, and steroid binding properties. This group of investigators has also shown that both chorion and amnion contain the aromatase complex ( Gibb and Lavoie, 1981 ). Thus, it is apparent that the fetal membranes have the full potential to synthesize estrogens and progesterone from DHEAS and P 5 S, a not surprising conclusion in view of the common trophoblastic origin of the placenta and chorion laeve. Amniotic fluid contains an abundant supply of steroidal sulfates that can serve as substrates for these biosynthetic enzymes, including DHEAS, 16-OH-DHEAS, pregnenolone, and 16 α -OH-P 5 S ( Schindler and Siiteri, 1968 ). Furthermore, the pattern of steroids found in amniotic fluid derived from fetal urine appears to closely reflect fetal adrenal secretory activity ( Sippell et al ., 1981 ). Older patients with mild defects in 3-beta–hydroxysteroid dehydrogenase activity (late-onset or nonclassic variant) may present with premature pubic hair development, hirsutism, irregular menstrual cycles or primary amenorrhea.

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Tecnologia IGBT x Mosfet. 通常,选择 IGBT 封装二极管以匹配其应用,具有较低正向传导损耗的较慢超快二极管和较慢的低 VCE (sat) 电机驱动 IGBT 封装。相比之下,软恢复超快二极管可以与高频 SMPS2 开关模式 IGBT 组合进行封装。除了选择合适的二极管外,设计人员还可以通过调整栅极驱动导通源阻抗来控制 Eon 损耗。降低驱动源阻抗将增加 IGBT 或 MOSFET 的开/关并降低 Eon 损耗。Eon 损耗和 EMI 需要妥协,因为更高的 di/dt 会导致电压尖峰,增加辐射和传导 EMI。为了选择正确的栅极驱动阻抗以满足开通 di/dt 要求,可能需要对电路进行内部测试和验证。 图 6:FCP11N60 (MOSFET):RDS (on) 与 IDRAIN 和 VGE 变化. 图 7:具有 ICE 和 Tj 变化的 IGBT Eoff. 结论: MOSFE 和IGBT没有本质区别。人们常问“MOSFET好还是IGBT好”的问题本身就是一个错误。为什么我们有时用MOSFET,有时用IGBT而不用MOSFET?不能简单地描述好坏的一面来区分和确定,需要用辩证的方法来考虑这个问题。 IGBT is a three-terminal semiconductor switching device used in various devices to amplify or switch between various electric signals. Its terminals are Collector, emitter, and gate. Since it is voltage controlled, it requires only a small amount of voltage to maintain conduction through the device. Sometimes, the body and source terminals are connected, bringing the terminal count down to 3. IGBT conducts charges through electrons and holes, whereas MOSFET carries charges through electrons. IGBTs are better at power handling than MOSFETs. IGBTs operate at a higher voltage rating than MOSFETs. Since MOSFETs have a thin metal oxide layer to separate the gate terminal, they are susceptible to electrostatic discharges. IGBTs, on the other hand, are more tolerant towards high voltages. Fire ganhar dinheiro casino jogos on line trade roleta on line Joker.

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